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Ovarian cancer: The word cancer still causes fear among people, especially when it is about diseases to the reproductive organs of women. Ovary (ovary) cancer is one of the most complex types to gynecology, and there are still many questions about its risk factors. Especially knowing whether the body’s increased weight or high BMI (body mass index) can become a cause behind this deadly disease, it remains a matter of discussion.

Although obesity is an installed risk factor for many types of cancer such as breast and uterine cancer, the opinion of experts on ovary cancer is slightly mixed. Let’s know what experts say about this and what indications are given from medical research so far.

Ovary Cancer and BMI

Compared to other gynecological cancer, the relationship between ovary cancer and obesity is not so clear. Some studies have found that there is a weak but noticeable relationship between high BMI and ovary cancer.

In a case-control study made in Roswell Park Cancer Institute, it was found that high BMI did not show any special effect in women’s postmenopausal women, but in women before menopause, the BMI 30 or more, which was more than that of the Ovary was found to be more than that of cancer. = 2.19).

How can the risk of cancer be added to obesity?

Although this relationship has not been fully understood yet, some biological principles definitely show its possibilities. Adipose tissue produces hormones like estrogen. When this hormone is present in excessive amounts, it may promote certain types of cancer.

This link has been clearly seen in the case of uterine cancer, while in ovary cancer this effect is slightly less directly. Some recent studies have indicated that increased estrogen levels in the blood may increase the risk of some borderline or initial stage cancer.

Hormonal imbalance is also a possible factor

Obese- hormonal imbalances such as hypernemia, insulin-like growth factor (IGF-1) and increased levels of Androgenes have uncontrolled division of cells. It is believed that this process can give birth to epithelial ovary cancer – the most common type of ovary cancer.

Influence of genetic factor and hormone therapy

When understanding the impact of BMI, it is also necessary to keep in mind other risk factors. Especially in women taking postmenopausal hormone therapy, especially only in estrogen therapy, risk profiles may be different according to BMI.

In addition, women with genetic mutations like BRCA1 and BRCA2 can have a lifetime risk of ovary cancer by up to 70%. This risk is independent of their weight.

Obesity also affects treatment

Even if obesity ovary is not a direct cause of cancer, it definitely affects the severity of the disease, the reaction of treatment and the life expectancy of the patient. Research has found that women who have low BMI recovering quickly after surgery and have a higher 5 -year surveillance rate.

Disclaimer: This article is based on media reports, JBT does not confirm it.